An engineered riboswitch as a potential gene-regulatory platform for reducing antibacterial drug resistance.
نویسندگان
چکیده
Synthetic riboswitch containing aptamer is constructed in E. coli to regulate the expression of β-lactamase through small molecule-aptamer interactions, which sharply reduces the antibiotic resistance of the engineered bacteria.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 1 شماره
صفحات -
تاریخ انتشار 2011